The Effects of Marijuana on Alzheimer's Patients

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They call it the longest goodbye. According to the Delphi study, about 24 million people suffered from dementia in 2001 worldwide, and this number has doubled by 2020. Alzheimers is a disease that effects an individual, almost everyone can say they know. This neurological disease chips pieces away of what makes someone themself.

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                                                                                           As this disease continues to grow, researchers and                                                                                                  doctors have been working diligently to find a cure                                                                                                and treatment to slow the spreading.

In 2020 the Alzheimer Society Research Program approved a grant to a research student to further study the effects on Alzheimer patients when they initiate the use of cannabis. The Alzheimer Society Research Program works to fund researchers in helping to find a cure for this disease. The campaign explained that “Since the Program's start in 1989, we have invested over $67 million in grants and awards toward innovative research that brings us closer to a future without Alzheimer’s disease and other dementias.”.

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This organization has recently recognized the positive effects cannabis can have on the brain while fighting many diseases. Cannabis also contains this chemical called Curcumin. Which is actually found in a plant commonly used for Asian medicine. It has been used to treat anorexia, coryza, cough, hepatic diseases and sinusitis.

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This attacks the chemical produced by the body;  polyphenol. This chemical is often created in the liver, pancreas, brainstem and digestive tract.

Interestingly, the metabolism of curcumin generates

products such as THC. THC oddly enough retains antiinflammatory activity. This fights against the spread of the chemical compounds that are secreted through the body, that

allow for the growth of the disease. The study on Natural substances and Alzheimer's disease: From preclinical studies to evidence based medicine, by doctors Cesare Mancuso, Raffaella Siciliano, Eugenio Barone and Paolo Preziosi were able to find these connections in their research

A study of Efficacy of Cannabinoids in a Pre-Clinical Drug-Screening Platform for Alzheimer’s Disease by students at UCLA, lead by professors D. Schubert and Devin Kepchia, found many positives from components of Cannabis. Doctors often see growth of what are called N2a/A PPswe cells. However when the test groups were given caffeine, THC and nothing the results showed a decrease in these cells when THC was administered.

This chart produced by the research team shows the positive effects marijuana may have. Here you see that the higher concentrated compounds of cannabis, allowed for a higher survival rate of healthy cells.

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The study went on to explain that nine of the eleven cannabinoids found in Marijuana have the ability to protect cells in four distinct phenotypic neurodegeneration. They are able to remove intraneuronal Aβ, which in turn reduces negative effects such as; oxidative damage, and the loss of energy or support. 

In recent years the legalization of Marijuana has been in effect in now 18 U.S states. This has led to a quick growing interest into research on the chemical products that make the plant so unique. Research has now discovered the positive effects this plant may have on a magnitude of illness's. I believe these doctors are right when they infer "This is just the beginning.".